Volume 1 Issue 2
May  2005
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XU Li-wen, LIAO Chang-rong, WANG Rui-xuan, LIU Guang-feng. Pharmacodynamics of florfenicol against pustule disease of Haliotis diversicolor under experimental infection[J]. South China Fisheries Science, 2005, 1(2): 31-34.
Citation: XU Li-wen, LIAO Chang-rong, WANG Rui-xuan, LIU Guang-feng. Pharmacodynamics of florfenicol against pustule disease of Haliotis diversicolor under experimental infection[J]. South China Fisheries Science, 2005, 1(2): 31-34.
shu

Pharmacodynamics of florfenicol against pustule disease of Haliotis diversicolor under experimental infection

  • 1.

    South China Sea Fisheries Institute, Chinese Academy of Fishery Sciences, Guangzhou 510300, China

  • 2.

    College of Aqua-life Science and Technology, Shanghai Fisheries University, Shanghai 200090, China

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  • Received Date: March 15, 2005
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    • Abstract

  • The therapeutic effect of florfenicol, a novel-broad-spectrum antibiotic, against pustule disease of juvenile abalone Haliotis diversicolor Reeve was studied with Myroides odoratus (Flavobacterium odortum) NPB-03 isolate under experimental infection through immersion, wounding or injecting in foot muscle. The results showed that the NPB-03 isolate failed to infect abalone in immersion, and the symptom of pustule disease in wounding infection was more obvious than that in injecting. Florfenicol of 6 μg · mL-1 bath concentration could decrease effectively mortality in wounding infection, but it was 10 μg · mL-1 concentration for injecting infection to induce mortality. This result demonstrated it needs high-dose chemotherapeutic agents for diseased abalone infected with pathogenic bacteria.

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    • References (16)
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