Study on antioxidation, animal experiments of hyperglycemia and hyperlipemia of agaropectin from Gracilaria lemaneiformis

This paper aims at investigating the role agaropectin plays in hyperglycemia, hyperlipemia and antioxidation. We studied the cleaning effect of O2-, OH and DPPH, based on which vitro antioxidation was assessed. We also researched hyperglycemia and hyperlipidemia by making use of alloxan to build diabetic model, and hyperlipidemia fodder to build hyperlipemia model, and conducted animal experiments with different doses of agaropectin so as to assay fasting blood glucose, rats blood fats (TC, TG, HDL-C and LDL-C), as well as biochemical indexes of serums and livers. The study of vitro antioxidation reveals that agaropectin has antioxidant effect, functioning especially well on scavenging OH. Animal experiments show that agaropectin can significantly reduce fasting plasma glucose value in hyperglycemia mice, and decrease the content of TC, TG and LDL-C contained in hyperlipidemia rats, which indicates that agaropectin really has an effect on hyperglycemia and hyperlipemia.