Abstract: Weassessed the feasibility of using sole and binary fresh waste from shrimp (Litopenaeus vannamei） for the culture of sea cucumber (Stichopus monotuberculatus) by studying the effects of sole and binary shrimp waste on sea cucumber's survival rate, specific growth rate (SGR), fecal production rate (FPR), ammonia-nitrogen and nitrite-nitrogen productionsas well asthe variations of total organic matter (TOM) content in the feces comparing with thosein corresponding feeds. Sea cucumbers grew fastest when fed with a diet containing 20% outdoor shrimp waste and 80% indoor shrimp waste. In the same diet treatment, FPR in the nighttime was significantly higher thanin the daytime (P0.05). The highest and lowest average total FPR occurred in diet treatment E(80% outdoor shrimp waste and 20% indoor shrimp waste) and diet trement A(outdoor shrimp waste), respectively. Both the ammonia-nitrogen production and nitrite-nitrogen production of sea cucumbers in different diet treatments decreased gradually as the crude protein levels in different diets decreased.TOM content in each feeds decreased while that in the feces increased at first, and then decreased gradually, respectively. In each diet treatment, the TOM content in feces decreased to different extent compared with those in the corresponding feeds, indicating sea cucumber has the crude potential of reducing organic pollution of shrimp waste.