Abstract: In order to provide references for developing high-density breeding of Litopenaeus vannamei, we established eight progeny populations based on eight different broodstock populations to investigate the growth and survival of the inbred and hybrid offspring of L.vannamei at different stocking densities (80 ind · m^-2, 200 ind · m^-2, 400 ind · m^-2). The results show that stocking density had great effect on growth and survival of different populations (P < 0.05). At stocking density of 80 ind · m^-2, the specific growth rate was 8.29~10.38 g · d^-1average (9.29±2.14) g · d^-1 and the survival rate was 66.7%~96.7% average (82.9±10.5)%, significantly higher than those at stocking density of 200 ind · m^-2 and 400 ind · m^-2 (P < 0.05). The growth and survival rate of L.vannamei reduced with increasing stocking density. Significant difference was found in growth and survival among different offspring of L.vannamei at three stocking densities. SIS♀×SIS♂ grew fast, higher than average values by 11.7%, 17.9% and 10.4% at stocking densities of 80 ind · m^-2, 200 ind · m^-2 and 400 ind · m^-2, respectively. HD♀×YH♂ had higher survival rate which were higher than average values by 13.7%, 9.3% and 9.5% at three stocking densities of 80 ind · m^-2, 200 ind · m^-2 and 400 ind · m^-2, respectively. YH♀×ZX♂ and YH♀×K♂ showed superior phenotype traits of growth and survival rate. It is suggested that SIS♀×SIS♂, HD♀×YH♂, YH♀×ZX♂ and YH♀×K♂ could be kept as breeding materials for next selective breeding.