Abstract: Artificial breeding of Chinese sanguin (Hiatula chinensis) was described in this article. During breeding season, the broodstocks of Chinese sanguin could mature and naturally spawn in one week after they were collected from the wild and fed with rich algae in an indoor rearing tank. Under water temperature range of 26.0~ 28℃, cleavage of zygotes and morula occurred in 1 h and 5 h, respectively;trocophore and D-larvae occurred in 12 h and 19 h, respectively, after fertilization. The D-larvae were reared at a density of 1 indmL-1 and fed with different algae. When fed with alga Chlorella vulgaris, the larvae died gradually after 7 days' culture. When fed with Dicrateria zhanjiangensis at D-larvae and added with Platymonas subcordiformis along with Chaetoceros muelleri the larvae grew well. When D-larvae changed to early umbone veligers, the larvae grew at average 10 md-1 in shell length and started metamorphosis on the 17th day after rearing. The mean shell length of the spat grew at 87.5 md-1 and reached to 4625 m by 50 days' rearing after larval settlement and metamorphosis.